Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- AF-218-NA - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-11 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-11 in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
P20809
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Tumor necrosis factor, interleukin 11, and leukemia inhibitory factor produced by Langerhans cells in Langerhans cell histiocytosis.
Tumor necrosis factor, interleukin 11, and leukemia inhibitory factor produced by Langerhans cells in Langerhans cell histiocytosis.
Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells.
Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells.
Andersson By U, Tani E, Andersson U, Henter JI
Journal of pediatric hematology/oncology 2004 Nov;26(11):706-11
Journal of pediatric hematology/oncology 2004 Nov;26(11):706-11
Tumor necrosis factor, interleukin 11, and leukemia inhibitory factor produced by Langerhans cells in Langerhans cell histiocytosis.
Andersson By U, Tani E, Andersson U, Henter JI
Journal of pediatric hematology/oncology 2004 Nov;26(11):706-11
Journal of pediatric hematology/oncology 2004 Nov;26(11):706-11
Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells.
Dimitriadis E, Robb L, Salamonsen LA
Molecular human reproduction 2002 Jul;8(7):636-43
Molecular human reproduction 2002 Jul;8(7):636-43
Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells.
Dimitriadis E, Robb L, Salamonsen LA
Molecular human reproduction 2002 Jul;8(7):636-43
Molecular human reproduction 2002 Jul;8(7):636-43
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Cell Proliferation Induced by IL-11 and Neutralization by Human IL-11 Antibody. Recombinant Human IL-11 (Catalog # 218-IL) stimulates proliferation in the T11 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-11 (1 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human IL-11 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-218-NA). The ND50 is typically 0.02-0.06 µg/mL.