APR03464G

antibody from Leading Biology

Targeting: IL12RB2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

APR03464G

Provider

Leading Biology

Product name

IL12_2 Antibody (C-term)

Antibody type

Polyclonal

Description

The protein encoded by this gene is a type I transmembraneprotein identified as a subunit of the interleukin 12 receptorcomplex. The coexpression of this and IL12RB1 proteins was shown tolead to the formation of high-affinity IL12 binding sites andreconstitution of IL12 dependent signaling. The expression of thisgene is up-regulated by interferon gamma in Th1 cells, and plays arole in Th1 cell differentiation. The up-regulation of this gene isfound to be associated with a number of infectious diseases, suchas Crohn's disease and leprosy, which is thought to contribute tothe inflammatory response and host defense.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.