CABT-B071
antibody from Creative Diagnostics
Targeting: EXOC7
BLOM4, EXO70, Exo70p, KIAA1067, YJL085W
Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations [0]
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- Product number
- CABT-B071 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-EXOC7 monoclonal antibody, clone 80Y24G4
- Antibody type
- Monoclonal
- Description
- Exocyst complex (also known as the sec6/8 complex) is a multimeric complex that has been implicated to play a role in exocytosis. This complex is conserved from yeast to mammals and is composed of eight subunits (Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84). In the budding yeast Saccharomyces cerevisiae, mutations in these complex subunits promote cytoplasmic accumulation of secretory vesicles and affects polarized growth. In cultured Drosophila and mammlian cells, disruption of exocyst subunit function has been found to decrease neurite outgrowth and Golgi-to-plasma membrane vesicle trafficking. Furthermore, a delay in neuronal induction was observed in mouse embryos with deletion of the sec8 gene, suggesting that the exocyst complex may play a role in cell differentiation and polarized growth.
- Reactivity
- Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 80Y24G4
- Vial size
- 100_g
- Concentration
- 1mg/ml
- Storage
- Store at 4°C
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