Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN522355 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384), (full length) antibody
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-384, full length
- Isotype
- IgG
- Antibody clone number
- 1D6
- Vial size
- 100 μg
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Handling
- Aliquot to avoid repeated freezing and thawing.
Submitted references LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling.
MiR-124 inhibits the migration and invasion of ovarian cancer cells by targeting SphK1.
Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells.
Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells.
The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.
Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition.
Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9.
A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart.
Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells.
Sheu JJ, Lee CC, Hua CH, Li CI, Lai MT, Lee SC, Cheng J, Chen CM, Chan C, Chao SC, Chen JY, Chang JY, Lee CH
Oncogene 2014 Mar 13;33(11):1375-84
Oncogene 2014 Mar 13;33(11):1375-84
MiR-124 inhibits the migration and invasion of ovarian cancer cells by targeting SphK1.
Zhang H, Wang Q, Zhao Q, Di W
Journal of ovarian research 2013 Nov 26;6(1):84
Journal of ovarian research 2013 Nov 26;6(1):84
Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells.
Böhm A, Flößer A, Ermler S, Fender AC, Lüth A, Kleuser B, Schrör K, Rauch BH
Cardiovascular research 2013 Aug 1;99(3):505-13
Cardiovascular research 2013 Aug 1;99(3):505-13
Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells.
Ali-Rahmani F, Hengst JA, Connor JR, Schengrund CL
Neurochemical research 2011 Sep;36(9):1687-96
Neurochemical research 2011 Sep;36(9):1687-96
The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.
Schröder M, Richter C, Juan MH, Maltusch K, Giegold O, Quintini G, Pfeilschifter JM, Huwiler A, Radeke HH
Molecular immunology 2011 May;48(9-10):1139-48
Molecular immunology 2011 May;48(9-10):1139-48
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.
Asher V, Warren A, Shaw R, Sowter H, Bali A, Khan R
Cancer cell international 2011 Mar 10;11:6
Cancer cell international 2011 Mar 10;11:6
Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition.
Sinha UK, Schorn VJ, Hochstim C, Chinn SB, Zhu S, Masood R
Head & neck 2011 Feb;33(2):178-88
Head & neck 2011 Feb;33(2):178-88
Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9.
Schenten V, Melchior C, Steinckwich N, Tschirhart EJ, Bréchard S
Journal of leukocyte biology 2011 Apr;89(4):587-96
Journal of leukocyte biology 2011 Apr;89(4):587-96
A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart.
Wang S, Zhang Z, Lin X, Xu DS, Feng Y, Ding K
Glycobiology 2010 Jan;20(4):473-84
Glycobiology 2010 Jan;20(4):473-84
Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells.
Billich A, Urtz N, Reuschel R, Baumruker T
The international journal of biochemistry & cell biology 2009 Jul;41(7):1547-55
The international journal of biochemistry & cell biology 2009 Jul;41(7):1547-55
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA