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- References [16]
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- Validations
- Western blot [1]
- Immunohistochemistry [3]
- Flow cytometry [1]
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- Product number
- ABIN446593 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Bovine, Zebrafish
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis.
Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.
Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.
A dual role for autophagy in a murine model of lung cancer.
Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells.
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma.
Augmenting autophagy to treat acute kidney injury during endotoxemia in mice.
Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells.
Macroautophagy abnormality in essential tremor.
Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity.
Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes.
Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation.
"Autophagic flux" in normal mouse tissues: focus on endogenous LC3A processing.
Silica nanoconstruct cellular toleration threshold in vitro.
Pathogenic lysosomal depletion in Parkinson's disease.
Saito T, Asai K, Sato S, Hayashi M, Adachi A, Sasaki Y, Takano H, Mizuno K, Shimizu W
Autophagy 2016;12(3):579-87
Autophagy 2016;12(3):579-87
Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.
Kohler LJ, Reed ShC, Sarraf SA, Arteaga DD, Newton HJ, Roy CR
mBio 2016 Jul 19;7(4)
mBio 2016 Jul 19;7(4)
Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.
Campos T, Ziehe J, Palma M, Escobar D, Tapia JC, Pincheira R, Castro AF
Molecular carcinogenesis 2016 Feb;55(2):220-9
Molecular carcinogenesis 2016 Feb;55(2):220-9
A dual role for autophagy in a murine model of lung cancer.
Rao S, Tortola L, Perlot T, Wirnsberger G, Novatchkova M, Nitsch R, Sykacek P, Frank L, Schramek D, Komnenovic V, Sigl V, Aumayr K, Schmauss G, Fellner N, Handschuh S, Glösmann M, Pasierbek P, Schlederer M, Resch GP, Ma Y, Yang H, Popper H, Kenner L, Kroemer G, Penninger JM
Nature communications 2014;5:3056
Nature communications 2014;5:3056
Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells.
Bruntz RC, Taylor HE, Lindsley CW, Brown HA
The Journal of biological chemistry 2014 Jan 10;289(2):600-16
The Journal of biological chemistry 2014 Jan 10;289(2):600-16
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
Yang A, Rajeshkumar NV, Wang X, Yabuuchi S, Alexander BM, Chu GC, Von Hoff DD, Maitra A, Kimmelman AC
Cancer discovery 2014 Aug;4(8):905-13
Cancer discovery 2014 Aug;4(8):905-13
mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma.
Giovannini M, Bonne NX, Vitte J, Chareyre F, Tanaka K, Adams R, Fisher LM, Valeyrie-Allanore L, Wolkenstein P, Goutagny S, Kalamarides M
Neuro-oncology 2014 Apr;16(4):493-504
Neuro-oncology 2014 Apr;16(4):493-504
Augmenting autophagy to treat acute kidney injury during endotoxemia in mice.
Howell GM, Gomez H, Collage RD, Loughran P, Zhang X, Escobar DA, Billiar TR, Zuckerbraun BS, Rosengart MR
PloS one 2013;8(7):e69520
PloS one 2013;8(7):e69520
Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells.
Santoni M, Amantini C, Morelli MB, Liberati S, Farfariello V, Nabissi M, Bonfili L, Eleuteri AM, Mozzicafreddo M, Burattini L, Berardi R, Cascinu S, Santoni G
British journal of cancer 2013 Aug 20;109(4):1040-50
British journal of cancer 2013 Aug 20;109(4):1040-50
Macroautophagy abnormality in essential tremor.
Kuo SH, Tang G, Ma K, Babij R, Cortes E, Vonsattel JP, Faust PL, Sulzer D, Louis ED
PloS one 2012;7(12):e53040
PloS one 2012;7(12):e53040
Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity.
Jeong JK, Moon MH, Bae BC, Lee YJ, Seol JW, Kang HS, Kim JS, Kang SJ, Park SY
Neuroscience research 2012 Jun;73(2):99-105
Neuroscience research 2012 Jun;73(2):99-105
Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes.
Schwarz L, Goldbaum O, Bergmann M, Probst-Cousin S, Richter-Landsberg C
Journal of molecular neuroscience : MN 2012 Jun;47(2):256-66
Journal of molecular neuroscience : MN 2012 Jun;47(2):256-66
Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation.
Chang CF, Huang HJ, Lee HC, Hung KC, Wu RT, Lin AM
Journal of pineal research 2012 Apr;52(3):312-21
Journal of pineal research 2012 Apr;52(3):312-21
"Autophagic flux" in normal mouse tissues: focus on endogenous LC3A processing.
Zois CE, Giatromanolaki A, Sivridis E, Papaiakovou M, Kainulainen H, Koukourakis MI
Autophagy 2011 Nov;7(11):1371-8
Autophagy 2011 Nov;7(11):1371-8
Silica nanoconstruct cellular toleration threshold in vitro.
Herd HL, Malugin A, Ghandehari H
Journal of controlled release : official journal of the Controlled Release Society 2011 Jul 15;153(1):40-8
Journal of controlled release : official journal of the Controlled Release Society 2011 Jul 15;153(1):40-8
Pathogenic lysosomal depletion in Parkinson's disease.
Dehay B, Bové J, Rodríguez-Muela N, Perier C, Recasens A, Boya P, Vila M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12535-44
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12535-44
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