FNab00675

antibody from FineTest Biotech

Targeting: ATG4C APG4C, AUTL1, AUTL3, FLJ14867

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: FNab00675 - Provider product page
Provider: FineTest Biotech
Product name: ATG4C antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ATG4 autophagy related 4 homolog C
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ATG4C protein structure - FNab00675 shown in red.