Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- HPA013189 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA013189, RRID:AB_10601215
- Product name
- Anti-TCF21
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TCF21, Gene description: transcription factor 21, Alternative Gene Names: bHLHa23, POD1, Validated applications: WB, Uniprot ID: O43680, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue
Protocol to generate cardiac pericytes from human induced pluripotent stem cells
Single-cell analysis of human fetal epicardium reveals its cellular composition and identifies CRIP1 as a modulator of EMT
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping
Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions
Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis
BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells
Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
Lock R, Graney P, Tavakol D, Nash T, Kim Y, Sanchez E, Morsink M, Ning D, Chen C, Fleischer S, Baldassarri I, Vunjak-Novakovic G
Cell Reports 2024;43(6):114302
Cell Reports 2024;43(6):114302
Protocol to generate cardiac pericytes from human induced pluripotent stem cells
Shen M, Zhao S, Khokhar Y, Li L, Zhou Y, Liu C, Wu J
STAR Protocols 2023;4(2):102256
STAR Protocols 2023;4(2):102256
Single-cell analysis of human fetal epicardium reveals its cellular composition and identifies CRIP1 as a modulator of EMT
Streef T, Groeneveld E, van Herwaarden T, Hjortnaes J, Goumans M, Smits A
Stem Cell Reports 2023;18(7):1421-1435
Stem Cell Reports 2023;18(7):1421-1435
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping
Zhao Q, Dacre M, Nguyen T, Pjanic M, Liu B, Iyer D, Cheng P, Wirka R, Kim J, Fraser H, Quertermous T
Genome Biology 2020;21(1)
Genome Biology 2020;21(1)
Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions
Kim J, Zhao Q, Nguyen T, Pjanic M, Cheng P, Wirka R, Travisano S, Nagao M, Kundu R, Quertermous T
Circulation 2020;142(6):575-590
Circulation 2020;142(6):575-590
Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration
Bargehr J, Ong L, Colzani M, Davaapil H, Hofsteen P, Bhandari S, Gambardella L, Le Novère N, Iyer D, Sampaziotis F, Weinberger F, Bertero A, Leonard A, Bernard W, Martinson A, Figg N, Regnier M, Bennett M, Murry C, Sinha S
Nature Biotechnology 2019;37(8):895-906
Nature Biotechnology 2019;37(8):895-906
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis
Wirka R, Wagh D, Paik D, Pjanic M, Nguyen T, Miller C, Kundu R, Nagao M, Coller J, Koyano T, Fong R, Woo Y, Liu B, Montgomery S, Wu J, Zhu K, Chang R, Alamprese M, Tallquist M, Kim J, Quertermous T
Nature Medicine 2019;25(8):1280-1289
Nature Medicine 2019;25(8):1280-1289
BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium
Gambardella L, McManus S, Moignard V, Sebukhan D, Delaune A, Andrews S, Bernard W, Morrison M, Riley P, Göttgens B, Gambardella Le Novère N, Sinha S
Development 2019;146(24)
Development 2019;146(24)
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells
Bosco G, Kim J, Pjanic M, Nguyen T, Miller C, Iyer D, Liu B, Wang T, Sazonova O, Carcamo-Orive I, Matic L, Maegdefessel L, Hedin U, Quertermous T
PLOS Genetics 2017;13(5):e1006750
PLOS Genetics 2017;13(5):e1006750
Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions
Bao X, Lian X, Qian T, Bhute V, Han T, Palecek S
Nature Protocols 2017;12(9):1890-1900
Nature Protocols 2017;12(9):1890-1900
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Miller C, Pjanic M, Wang T, Nguyen T, Cohain A, Lee J, Perisic L, Hedin U, Kundu R, Majmudar D, Kim J, Wang O, Betsholtz C, Ruusalepp A, Franzén O, Assimes T, Montgomery S, Schadt E, Björkegren J, Quertermous T
Nature Communications 2016;7(1)
Nature Communications 2016;7(1)
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci
McCarthy M, Sazonova O, Zhao Y, Nürnberg S, Miller C, Pjanic M, Castano V, Kim J, Salfati E, Kundaje A, Bejerano G, Assimes T, Yang X, Quertermous T
PLOS Genetics 2015;11(5):e1005202
PLOS Genetics 2015;11(5):e1005202
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
McCarthy M, Nurnberg S, Cheng K, Raiesdana A, Kundu R, Miller C, Kim J, Arora K, Carcamo-Oribe I, Xiong Y, Tellakula N, Nanda V, Murthy N, Boisvert W, Hedin U, Perisic L, Aldi S, Maegdefessel L, Pjanic M, Owens G, Tallquist M, Quertermous T
PLOS Genetics 2015;11(5):e1005155
PLOS Genetics 2015;11(5):e1005155
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