Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00025797-A01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00025797-A01, RRID:AB_669287
- Product name
- Mouse Polyclonal Glutaminyl-peptide Cyclotransferase/QPCT Antibody
- Antibody type
- Polyclonal
- Description
- Glutaminyl-peptide Cyclotransferase/QPCT
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-β load and cognitive decline in Alzheimer's disease.
Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins.
Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms.
Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease.
Morawski M, Schilling S, Kreuzberger M, Waniek A, Jäger C, Koch B, Cynis H, Kehlen A, Arendt T, Hartlage-Rübsamen M, Demuth HU, Roßner S
Journal of Alzheimer's disease : JAD 2014;39(2):385-400
Journal of Alzheimer's disease : JAD 2014;39(2):385-400
Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins.
Chen YL, Huang KF, Kuo WC, Lo YC, Lee YM, Wang AH
The Biochemical journal 2012 Mar 1;442(2):403-12
The Biochemical journal 2012 Mar 1;442(2):403-12
Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms.
Hartlage-Rübsamen M, Morawski M, Waniek A, Jäger C, Zeitschel U, Koch B, Cynis H, Schilling S, Schliebs R, Demuth HU, Rossner S
Acta neuropathologica 2011 Jun;121(6):705-19
Acta neuropathologica 2011 Jun;121(6):705-19
Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease.
Morawski M, Hartlage-Rübsamen M, Jäger C, Waniek A, Schilling S, Schwab C, McGeer PL, Arendt T, Demuth HU, Rossner S
Acta neuropathologica 2010 Aug;120(2):195-207
Acta neuropathologica 2010 Aug;120(2):195-207
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [H00025797-A01] - Detection against Immunogen (36.89 KDa) .