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- References [5]
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- Product number
- ABIN394702 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Glutaminyl-Peptide Cyclotransferase (QPCT) (AA 262-360) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 262-360
- Isotype
- IgG
- Antibody clone number
- 4E11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics.
A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.
Computational evidence for the catalytic mechanism of glutaminyl cyclase. A DFT investigation.
Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.
A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Stephan A, Wermann M, von Bohlen A, Koch B, Cynis H, Demuth HU, Schilling S
The FEBS journal 2009 Nov;276(22):6522-36
The FEBS journal 2009 Nov;276(22):6522-36
A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.
Marroni F, Pfeufer A, Aulchenko YS, Franklin CS, Isaacs A, Pichler I, Wild SH, Oostra BA, Wright AF, Campbell H, Witteman JC, Kääb S, Hicks AA, Gyllensten U, Rudan I, Meitinger T, Pattaro C, van Duijn CM, Wilson JF, Pramstaller PP, EUROSPAN Consortium.
Circulation. Cardiovascular genetics 2009 Aug;2(4):322-8
Circulation. Cardiovascular genetics 2009 Aug;2(4):322-8
Computational evidence for the catalytic mechanism of glutaminyl cyclase. A DFT investigation.
Calvaresi M, Garavelli M, Bottoni A
Proteins 2008 Nov 15;73(3):527-38
Proteins 2008 Nov 15;73(3):527-38
Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.
Cynis H, Rahfeld JU, Stephan A, Kehlen A, Koch B, Wermann M, Demuth HU, Schilling S
Journal of molecular biology 2008 Jun 20;379(5):966-80
Journal of molecular biology 2008 Jun 20;379(5):966-80
A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Huang KF, Wang YR, Chang EC, Chou TL, Wang AH
The Biochemical journal 2008 Apr 1;411(1):181-90
The Biochemical journal 2008 Apr 1;411(1):181-90
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
