Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [4]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN2850439 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719), (Loop 2) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 689-719, Loop 2
- Antibody clone number
- RB14211
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer.
Long-term culture of genome-stable bipotent stem cells from adult human liver.
Characterization of Three-Dimensional Retinal Tissue Derived from Human Embryonic Stem Cells in Adherent Monolayer Cultures.
The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells.
LGR5 is a promising biomarker for patients with stage I and II gastric cancer.
Intestinal stem cell marker LGR5 expression during gastric carcinogenesis.
Transcription factor Oct1 is a somatic and cancer stem cell determinant.
Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling.
Significance of Lgr5(+ve) cancer stem cells in the colon and rectum.
Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3.
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Jardé T, Kass L, Staples M, Lescesen H, Carne P, Oliva K, McMurrick PJ, Abud HE
PloS one 2015;10(9):e0138336
PloS one 2015;10(9):e0138336
Long-term culture of genome-stable bipotent stem cells from adult human liver.
Huch M, Gehart H, van Boxtel R, Hamer K, Blokzijl F, Verstegen MM, Ellis E, van Wenum M, Fuchs SA, de Ligt J, van de Wetering M, Sasaki N, Boers SJ, Kemperman H, de Jonge J, Ijzermans JN, Nieuwenhuis EE, Hoekstra R, Strom S, Vries RR, van der Laan LJ, Cuppen E, Clevers H
Cell 2015 Jan 15;160(1-2):299-312
Cell 2015 Jan 15;160(1-2):299-312
Characterization of Three-Dimensional Retinal Tissue Derived from Human Embryonic Stem Cells in Adherent Monolayer Cultures.
Singh RK, Mallela RK, Cornuet PK, Reifler AN, Chervenak AP, West MD, Wong KY, Nasonkin IO
Stem cells and development 2015 Dec 1;24(23):2778-95
Stem cells and development 2015 Dec 1;24(23):2778-95
The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells.
Ying J, Tsujii M, Kondo J, Hayashi Y, Kato M, Akasaka T, Inoue T, Shiraishi E, Inoue T, Hiyama S, Tsujii Y, Maekawa A, Kawai S, Fujinaga T, Araki M, Shinzaki S, Watabe K, Nishida T, Iijima H, Takehara T
International journal of oncology 2015 Apr;46(4):1551-9
International journal of oncology 2015 Apr;46(4):1551-9
LGR5 is a promising biomarker for patients with stage I and II gastric cancer.
Bu Z, Zheng Z, Zhang L, Li Z, Sun Y, Dong B, Wu A, Wu X, Wang X, Cheng X, Xing X, Li Y, Du H, Ji J
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2013 Feb;25(1):79-89
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2013 Feb;25(1):79-89
Intestinal stem cell marker LGR5 expression during gastric carcinogenesis.
Zheng ZX, Sun Y, Bu ZD, Zhang LH, Li ZY, Wu AW, Wu XJ, Wang XH, Cheng XJ, Xing XF, Du H, Ji JF
World journal of gastroenterology 2013 Dec 14;19(46):8714-21
World journal of gastroenterology 2013 Dec 14;19(46):8714-21
Transcription factor Oct1 is a somatic and cancer stem cell determinant.
Maddox J, Shakya A, South S, Shelton D, Andersen JN, Chidester S, Kang J, Gligorich KM, Jones DA, Spangrude GJ, Welm BE, Tantin D
PLoS genetics 2012;8(11):e1003048
PLoS genetics 2012;8(11):e1003048
Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling.
Judah D, Rudkouskaya A, Wilson R, Carter DE, Dagnino L
PloS one 2012;7(5):e36704
PloS one 2012;7(5):e36704
Significance of Lgr5(+ve) cancer stem cells in the colon and rectum.
Takahashi H, Ishii H, Nishida N, Takemasa I, Mizushima T, Ikeda M, Yokobori T, Mimori K, Yamamoto H, Sekimoto M, Doki Y, Mori M
Annals of surgical oncology 2011 Apr;18(4):1166-74
Annals of surgical oncology 2011 Apr;18(4):1166-74
Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3.
Satoh J, Obayashi S, Tabunoki H, Wakana T, Kim SU
Cellular and molecular neurobiology 2010 Apr;30(3):415-26
Cellular and molecular neurobiology 2010 Apr;30(3):415-26
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H
Nature 2007 Oct 25;449(7165):1003-7
Nature 2007 Oct 25;449(7165):1003-7
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Supportive validation
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