FNab02527

antibody from FineTest Biotech

Targeting: DR1 NC2-BETA, NC2B, NCB2

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: FNab02527 - Provider product page
Provider: FineTest Biotech
Product name: DR1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

DR1 protein structure - FNab02527 shown in red.