BS2774

antibody from Bioworld Technology, Inc
Targeting: FZD7 FzE3
Provider product page for BS2774
Western blot
Immunocytochemistry

Antibody data

Product number
BS2774 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2774, RRID:AB_1662552
Product name
Frizzled 7 (Y87) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 61-110 of Human Frizzled-7.
Description
The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. frizzled-7 has a Lys-Thr-X-X-X-Trp motif which is involved in the activation of the Wnt/beta-catenin signaling pathway. frizzled-7 is an integral membrane protein showing a high expression in adult skeletal muscle, fetal kidney, fetal lung, adult heart, brain and placenta. It is specifically expressed in squamous cell esophageal carcinomas.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FZD7 protein structure - BS2774 shown in red.