BS7659

antibody from Bioworld Technology, Inc
Targeting: BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK
Provider product page for BS7659
Western blot
Immunohistochemistry

Antibody data

Product number
BS7659 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BMPR2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human BMPR2.
Description
Members of the transforming growth factor ÉÇ superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BMPR2 protein structure - BS7659 shown in red.