Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- PAB1907 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1907, RRID:AB_1571742
- Product name
- BMPR2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BMPR2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia.
Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension.
Jara A, Chacón C, Burgos ME, Droguett A, Valdivieso A, Ortiz M, Troncoso P, Mezzano S
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Apr;24(4):1121-9
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Apr;24(4):1121-9
Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension.
Sehgal PB, Mukhopadhyay S, Xu F, Patel K, Shah M
American journal of physiology. Lung cellular and molecular physiology 2007 Jun;292(6):L1526-42
American journal of physiology. Lung cellular and molecular physiology 2007 Jun;292(6):L1526-42
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BMPR2 polyclonal antibody (Cat # PAB1907) in mouse heart tissue lysate. BMPR2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of BMPR2 polyclonal antibody (Cat # PAB1907) in frozen section of human brain tissue.0.005 mg/mL primary antibody was followed by FITC-conjugated anti-rabbit antibody. FITC-conjugated anti-rabbit antibody emits green fluorescence. Blue counterstaining is Hoechst 33258.This image kindly offered by Chunqing Zhang, Third Military Medical University.
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocarcinoma (A) and human kidney (B) tissue reacted with BMPR2 polyclonal antibody (Cat # PAB1907), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of HepG2 cells using BMPR2 polyclonal antibody (Cat # PAB1907)(bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry