AMM02214G

antibody from Leading Biology

Targeting: BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02214G

Provider

Leading Biology

Product name

BMPR2 Antibody (clone 3F6)

Antibody type

Monoclonal

Description

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.

Reactivity

Human, Mouse, Rat, Simian

Host

Mouse

Antibody clone number

3F6

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.