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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- MAB6927 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB6927, RRID:AB_10677537
- Product name
- CTLA4 monoclonal antibody, clone ANC152.2/8H5
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against CTLA4.
- Isotype
- IgG
- Antibody clone number
- ANC152.2/8H5
- Storage
- Store at 4°C.
Submitted references CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells.
Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells.
CTLA-4: a negative regulator of autoimmune disease.
Zheng Y, Manzotti CN, Liu M, Burke F, Mead KI, Sansom DM
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 1;172(5):2778-84
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 1;172(5):2778-84
Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells.
Kitani A, Chua K, Nakamura K, Strober W
Journal of immunology (Baltimore, Md. : 1950) 2000 Jul 15;165(2):691-702
Journal of immunology (Baltimore, Md. : 1950) 2000 Jul 15;165(2):691-702
CTLA-4: a negative regulator of autoimmune disease.
Karandikar NJ, Vanderlugt CL, Walunas TL, Miller SD, Bluestone JA
The Journal of experimental medicine 1996 Aug 1;184(2):783-8
The Journal of experimental medicine 1996 Aug 1;184(2):783-8
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- CTLA4 monoclonal antibody, clone ANC152.2/8H5 (Cat # MAB6927) blocked the binding of recombinant CTLA4-muIg fusion protein/R-PE conjugate to CD80 and CD86 expressed on human Raji cells.
- Validation comment
- Flow Cytometry
