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- References [6]
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- Product number
- ABIN252918 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Goat
- Vial size
- 0.1 mg
- Storage
- Store at -20°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer.
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.
Collagen prolyl hydroxylases are essential for breast cancer metastasis.
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.
Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix.
Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.
Xiang L, Gilkes DM, Chaturvedi P, Luo W, Hu H, Takano N, Liang H, Semenza GL
Journal of molecular medicine (Berlin, Germany) 2014 Feb;92(2):151-64
Journal of molecular medicine (Berlin, Germany) 2014 Feb;92(2):151-64
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.
Xiang L, Gilkes DM, Hu H, Takano N, Luo W, Lu H, Bullen JW, Samanta D, Liang H, Semenza GL
Oncotarget 2014 Dec 30;5(24):12509-27
Oncotarget 2014 Dec 30;5(24):12509-27
Collagen prolyl hydroxylases are essential for breast cancer metastasis.
Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL
Cancer research 2013 Jun 1;73(11):3285-96
Cancer research 2013 Jun 1;73(11):3285-96
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.
Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL
The Journal of biological chemistry 2013 Apr 12;288(15):10819-29
The Journal of biological chemistry 2013 Apr 12;288(15):10819-29
Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix.
Van Duyn Graham L, Sweetwyne MT, Pallero MA, Murphy-Ullrich JE
The Journal of biological chemistry 2010 Mar 5;285(10):7067-78
The Journal of biological chemistry 2010 Mar 5;285(10):7067-78
Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.
Annunen P, Helaakoski T, Myllyharju J, Veijola J, Pihlajaniemi T, Kivirikko KI
The Journal of biological chemistry 1997 Jul 11;272(28):17342-8
The Journal of biological chemistry 1997 Jul 11;272(28):17342-8
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
