FNab00803

antibody from FineTest Biotech

Targeting: BARD1

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab00803 - Provider product page
Provider: FineTest Biotech
Product name: BARD1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: BRCA1 associated RING domain 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

BARD1 protein structure - FNab00803 shown in red.