BS8056

antibody from Bioworld Technology, Inc

Targeting: GNAI3 87U6

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8056

Provider

Bioworld Technology, Inc

Product name

GNAI3 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human GNAI3.

Description

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Ï«, ÉÇ and ÎÛ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Ï« subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of GÏ« subunits have been identified; these include Gs, Gi, Gq and GÏ« 12/13. The Gi class comprises all the known Ï« subunits that are susceptible to pertussis toxin modifications, including GÏ« i-1, GÏ« i-2, GÏ« i-3, GÏ« o, GÏ« t1, GÏ« t2, GÏ« z and GÏ« gust. Of these, the three GÏ« i subtypes function to open atrial potassium channels.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.