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antibody from Novus Biologicals
Targeting: ECM1
ELISA Immunocytochemistry Immunoprecipitation
Immunohistochemistry Flow cytometry Immunoelectron microscopyAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [3]
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- Product number
- NBP2-29464 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal ECM-1/Secretory Component P85 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
- Reactivity
- Human, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
Submitted references Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease.
Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease.
Polymeric immunoglobulin receptor-negative tumors represent a more aggressive type of adenocarcinomas of distal esophagus and gastroesophageal junction.
Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity.
Differential expression of immunobiological mediators by immortalized human cervical and vaginal epithelial cells.
Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins.
Keratin 19 expression in the adult and developing human mammary gland.
Philley JV, Kannan A, Griffith DE, Devine MS, Benwill JL, Wallace RJ Jr, Brown-Elliott BA, Thakkar F, Taskar V, Fox JG, Alqaid A, Bains H, Gupta S, Dasgupta S
Oncotarget 2017 Mar 14;8(11):18070-18081
Oncotarget 2017 Mar 14;8(11):18070-18081
Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease.
Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS
American journal of respiratory and critical care medicine 2011 Aug 1;184(3):317-27
American journal of respiratory and critical care medicine 2011 Aug 1;184(3):317-27
Polymeric immunoglobulin receptor-negative tumors represent a more aggressive type of adenocarcinomas of distal esophagus and gastroesophageal junction.
Gologan A, Acquafondata M, Dhir R, Sepulveda AR
Archives of pathology & laboratory medicine 2008 Aug;132(8):1295-301
Archives of pathology & laboratory medicine 2008 Aug;132(8):1295-301
Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity.
Tang QJ, Tao KZ, Yun-Liu, Sun XJ, Geng MY, Jiang CL
Journal of molecular histology 2005 Jun;36(5):331-5
Journal of molecular histology 2005 Jun;36(5):331-5
Differential expression of immunobiological mediators by immortalized human cervical and vaginal epithelial cells.
Fichorova RN, Anderson DJ
Biology of reproduction 1999 Feb;60(2):508-14
Biology of reproduction 1999 Feb;60(2):508-14
Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins.
Fichorova RN, Rheinwald JG, Anderson DJ
Biology of reproduction 1997 Oct;57(4):847-55
Biology of reproduction 1997 Oct;57(4):847-55
Keratin 19 expression in the adult and developing human mammary gland.
Bartek J, Bartkova J, Taylor-Papadimitriou J
The Histochemical journal 1990 Oct;22(10):537-44
The Histochemical journal 1990 Oct;22(10):537-44
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ECM-1/Secretory Component P85 Antibody (SC05) [NBP2-29464] - Secretory Component / ECM1 Antibody (SC05) [NBP2-29464] - Formalin-fixed, paraffin-embedded normal human intestine (20X) stained with MUC2 antibody (1:200), peroxidase-conjugate and DAB chromogen.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ECM-1/Secretory Component P85 Antibody (SC05) [NBP2-29464] - Secretory Component / ECM1 Antibody (SC05) [NBP2-29464] - Staining of normal human small intestine. Note cytoplasmic and membrane staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ECM-1/Secretory Component P85 Antibody (SC05) [NBP2-29464] - Formalin-fixed, paraffin-embedded normal human intestine (10X) stained with MUC2 antibody (1:200), peroxidase-conjugate and DAB chromogen.
