PAB14845

antibody from Abnova Corporation

Targeting: GREM1 CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

PAB14845

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB14845, RRID:AB_10680827

Product name

GREM1 polyclonal antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to amino acids at C-terminus of human GREM1.

Reactivity

Human

Host

Rabbit

Vial size

100 µg

Storage

Store at -20°C on dry atmosphere.After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Expression of gremlin 1 correlates with increased angiogenesis and progression-free survival in patients with pancreatic neuroendocrine tumors.

Chen MH, Yeh YC, Shyr YM, Jan YH, Chao Y, Li CP, Wang SE, Tzeng CH, Chang PM, Liu CY, Chen MH, Hsiao M, Huang CY
Journal of gastroenterology 2013 Jan;48(1):101-8

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Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor.

Stabile H, Mitola S, Moroni E, Belleri M, Nicoli S, Coltrini D, Peri F, Pessi A, Orsatti L, Talamo F, Castronovo V, Waltregny D, Cotelli F, Ribatti D, Presta M
Blood 2007 Mar 1;109(5):1834-40

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The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein.

Namkoong H, Shin SM, Kim HK, Ha SA, Cho GW, Hur SY, Kim TE, Kim JW
BMC cancer 2006 Mar 18;6:74

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Skeletal overexpression of gremlin impairs bone formation and causes osteopenia.

Gazzerro E, Pereira RC, Jorgetti V, Olson S, Economides AN, Canalis E
Endocrinology 2005 Feb;146(2):655-65