ABIN2840598
antibody from antibodies-online
Targeting: GREM1
CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS
Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN2840598 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Gremlin 1 (GREM1) (AA 147-175), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 147-175, C-Term
- Antibody clone number
- RB2060
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Gremlin is a key pro-fibrogenic factor in chronic pancreatitis.
Tubular overexpression of gremlin induces renal damage susceptibility in mice.
Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma.
Molecular differentiation between osteophytic and articular cartilage--clues for a transient and permanent chondrocyte phenotype.
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.
Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia.
Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy.
Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma.
Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis.
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
Staloch D, Gao X, Liu K, Xu M, Feng X, Aronson JF, Falzon M, Greeley GH, Rastellini C, Chao C, Hellmich MR, Cao Y, Ko TC
Journal of molecular medicine (Berlin, Germany) 2015 Oct;93(10):1085-1093
Journal of molecular medicine (Berlin, Germany) 2015 Oct;93(10):1085-1093
Tubular overexpression of gremlin induces renal damage susceptibility in mice.
Droguett A, Krall P, Burgos ME, Valderrama G, Carpio D, Ardiles L, Rodriguez-Diez R, Kerr B, Walz K, Ruiz-Ortega M, Egido J, Mezzano S
PloS one 2014;9(7):e101879
PloS one 2014;9(7):e101879
Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma.
Ahn EH, Mercado GE, Laé M, Ladanyi M
Oncology reports 2013 Aug;30(2):968-78
Oncology reports 2013 Aug;30(2):968-78
Molecular differentiation between osteophytic and articular cartilage--clues for a transient and permanent chondrocyte phenotype.
Gelse K, Ekici AB, Cipa F, Swoboda B, Carl HD, Olk A, Hennig FF, Klinger P
Osteoarthritis and cartilage 2012 Feb;20(2):162-71
Osteoarthritis and cartilage 2012 Feb;20(2):162-71
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, Ferguson DJ, Campbell BJ, Jewell D, Simmons A
Nature medicine 2010 Jan;16(1):90-7
Nature medicine 2010 Jan;16(1):90-7
Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia.
Jara A, Chacón C, Burgos ME, Droguett A, Valdivieso A, Ortiz M, Troncoso P, Mezzano S
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Apr;24(4):1121-9
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Apr;24(4):1121-9
Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy.
Carvajal G, Droguett A, Burgos ME, Aros C, Ardiles L, Flores C, Carpio D, Ruiz-Ortega M, Egido J, Mezzano S
Transplantation proceedings 2008 Apr;40(3):734-9
Transplantation proceedings 2008 Apr;40(3):734-9
Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma.
Wordinger RJ, Fleenor DL, Hellberg PE, Pang IH, Tovar TO, Zode GS, Fuller JA, Clark AF
Investigative ophthalmology & visual science 2007 Mar;48(3):1191-200
Investigative ophthalmology & visual science 2007 Mar;48(3):1191-200
Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis.
Mezzano S, Droguett A, Burgos ME, Aros C, Ardiles L, Flores C, Carpio D, Carvajal G, Ruiz-Ortega M, Egido J
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Jul;22(7):1882-90
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Jul;22(7):1882-90
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
Frank NY, Kho AT, Schatton T, Murphy GF, Molloy MJ, Zhan Q, Ramoni MF, Frank MH, Kohane IS, Gussoni E
The Journal of cell biology 2006 Oct 9;175(1):99-110
The Journal of cell biology 2006 Oct 9;175(1):99-110
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC