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- References [6]
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- Western blot [2]
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- Product number
- H00029956-M01A - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00029956-M01A, RRID:AB_2132954
- Product name
- Mouse Monoclonal LASS2 Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. LASS2 - LAG1 longevity assurance homolog 2 (S. cerevisiae) (1A6)
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgM
- Vial size
- 0.2 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease.
SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.
Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism.
The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis.
Couttas TA, Kain N, Suchowerska AK, Quek LE, Turner N, Fath T, Garner B, Don AS
Neurobiology of aging 2016 Jul;43:89-100
Neurobiology of aging 2016 Jul;43:89-100
SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
Novgorodov SA, Riley CL, Keffler JA, Yu J, Kindy MS, Macklin WB, Lombard DB, Gudz TI
The Journal of biological chemistry 2016 Jan 22;291(4):1957-73
The Journal of biological chemistry 2016 Jan 22;291(4):1957-73
Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI
Anticancer research 2012 Mar;32(3):753-60
Anticancer research 2012 Mar;32(3):753-60
siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.
Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI
Anticancer research 2012 Jul;32(7):2479-2485
Anticancer research 2012 Jul;32(7):2479-2485
Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism.
Mullen TD, Spassieva S, Jenkins RW, Kitatani K, Bielawski J, Hannun YA, Obeid LM
Journal of lipid research 2011 Jan;52(1):68-77
Journal of lipid research 2011 Jan;52(1):68-77
The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis.
Siskind LJ, Mullen TD, Romero Rosales K, Clarke CJ, Hernandez-Corbacho MJ, Edinger AL, Obeid LM
The Journal of biological chemistry 2010 Apr 16;285(16):11818-26
The Journal of biological chemistry 2010 Apr 16;285(16):11818-26
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LASS2 Antibody (1A6) [H00029956-M01A] - S2 monoclonal antibody (M01), clone 1A6 Western Blot analysis of LASS2 expression in HepG2.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LASS2 Antibody (1A6) [H00029956-M01A] - Human neuroblastoma cells untreated or treated with various drugs. Image from verified customer review.
