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- Antigen structure
- References [11]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 14899-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14899-1-AP, RRID:AB_2170627
- Product name
- PSMD4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PSMD4 antibody (Cat. #14899-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells.
Generation and identification of a conditional knockout allele for the PSMD11 gene in mice.
Proteaphagy in Mammalian Cells Can Function Independent of ATG5/ATG7.
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations.
Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium.
Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance.
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
S5a binds to death receptor-6 to induce THP-1 monocytes to differentiate through the activation of the NF-κB pathway.
Interaction of HPV E6 oncoproteins with specific proteasomal subunits.
Benvenuto M, Ciuffa S, Focaccetti C, Sbardella D, Fazi S, Scimeca M, Tundo GR, Barillari G, Segni M, Bonanno E, Manzari V, Modesti A, Masuelli L, Coletta M, Bei R
Scientific reports 2021 Sep 24;11(1):19051
Scientific reports 2021 Sep 24;11(1):19051
Generation and identification of a conditional knockout allele for the PSMD11 gene in mice.
Zhao L, Zhao J, Zhang Y, Wang L, Zuo L, Niu A, Zhang W, Xue X, Zhao S, Sun C, Li K, Wang J, Bian Z, Zhao X, Saur D, Seidler B, Wang C, Qi T
BMC developmental biology 2021 Feb 1;21(1):4
BMC developmental biology 2021 Feb 1;21(1):4
Proteaphagy in Mammalian Cells Can Function Independent of ATG5/ATG7.
Goebel T, Mausbach S, Tuermer A, Eltahir H, Winter D, Gieselmann V, Thelen M
Molecular & cellular proteomics : MCP 2020 Jul;19(7):1120-1131
Molecular & cellular proteomics : MCP 2020 Jul;19(7):1120-1131
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations.
Sbardella D, Tundo GR, Cunsolo V, Grasso G, Cascella R, Caputo V, Santoro AM, Milardi D, Pecorelli A, Ciaccio C, Di Pierro D, Leoncini S, Campagnolo L, Pironi V, Oddone F, Manni P, Foti S, Giardina E, De Felice C, Hayek J, Curatolo P, Galasso C, Valacchi G, Coletta M, Graziani G, Marini S
Biochimica et biophysica acta. Molecular basis of disease 2020 Jul 1;1866(7):165793
Biochimica et biophysica acta. Molecular basis of disease 2020 Jul 1;1866(7):165793
Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.
Avagliano Trezza R, Sonzogni M, Bossuyt SNV, Zampeta FI, Punt AM, van den Berg M, Rotaru DC, Koene LMC, Munshi ST, Stedehouder J, Kros JM, Williams M, Heussler H, de Vrij FMS, Mientjes EJ, van Woerden GM, Kushner SA, Distel B, Elgersma Y
Nature neuroscience 2019 Aug;22(8):1235-1247
Nature neuroscience 2019 Aug;22(8):1235-1247
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Liu X, Chen L, Ge J, Yan C, Huang Z, Hu J, Wen C, Li M, Huang D, Qiu Y, Hao H, Yuan R, Lei J, Yu X, Shao J
Cancer research 2016 Aug 15;76(16):4897-907
Cancer research 2016 Aug 15;76(16):4897-907
The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium.
Gerhardt C, Lier JM, Burmühl S, Struchtrup A, Deutschmann K, Vetter M, Leu T, Reeg S, Grune T, Rüther U
The Journal of cell biology 2015 Jul 6;210(1):115-33
The Journal of cell biology 2015 Jul 6;210(1):115-33
Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance.
Nanduri P, Hao R, Fitzpatrick T, Yao TP
The Journal of biological chemistry 2015 Apr 10;290(15):9455-64
The Journal of biological chemistry 2015 Apr 10;290(15):9455-64
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Sparks A, Dayal S, Das J, Robertson P, Menendez S, Saville MK
Oncogene 2014 Sep 18;33(38):4685-96
Oncogene 2014 Sep 18;33(38):4685-96
S5a binds to death receptor-6 to induce THP-1 monocytes to differentiate through the activation of the NF-κB pathway.
Wang Z, Fan C, Zhou HF, Lu JS, Sun MJ, Song JW, Le Y, Jiang HD, Wang LH, Jiao BH
Journal of cell science 2014 Aug 1;127(Pt 15):3257-68
Journal of cell science 2014 Aug 1;127(Pt 15):3257-68
Interaction of HPV E6 oncoproteins with specific proteasomal subunits.
Tomaić V, Ganti K, Pim D, Bauer C, Blattner C, Banks L
Virology 2013 Nov;446(1-2):389-96
Virology 2013 Nov;446(1-2):389-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 14899-1-AP(PSMD4 antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using PSMD4 antibody 14899-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
