66220-1-Ig

antibody from Proteintech Group

Targeting: PDCD1 CD279, hSLE1, PD-1, PD1, SLEB2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

66220-1-Ig

Provider

Proteintech Group

Product name

PD-1/CD279 antibody

Antibody type

Monoclonal

Description

PD-1/CD279 antibody (Cat. #66220-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4H4D1

Vial size

20ul, 150ul

References

Submitted references

The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.

Shen Y, Li Y, Zhu Q, Wang J, Huang Y, Liang J, Wu X, Zhao Y
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63

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Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma.

Nasarre P, Garcia DI, Siegel JB, Bonilla IV, Mukherjee R, Hilliard E, Chakraborty P, Nasarre C, Yustein JT, Lang M, Jaffa AA, Mehrotra S, Klauber-DeMore N
Cancers 2021 May 30;13(11)

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The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin‑induced cardiotoxicity.

Kanno SI, Hara A
Molecular medicine reports 2021 Feb;23(2)

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Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma.

Xu W, Li S, Li M, Yang X, Xie S, Lin L, Li G, Zhou H
Immunology letters 2021 Dec;240:31-40

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Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma.

Cao JY, Guo Q, Guan GF, Zhu C, Zou CY, Zhang LY, Cheng W, Wang GL, Cheng P, Wu AH, Li GY
Aging 2020 Jan 29;12(2):1656-1684

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Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin.

Zhang S, Zhou L, Zhang M, Wang Y, Wang M, Du J, Gu W, Kui F, Li J, Geng S, Du G
Frontiers in pharmacology 2019;10:1658

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Survival analysis with regard to PD-L1 and CD155 expression in human small cell lung cancer and a comparison with associated receptors.

Xu Y, Cui G, Jiang Z, Li N, Zhang X
Oncology letters 2019 Mar;17(3):2960-2968

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m⁶A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY
Nature communications 2019 Jun 25;10(1):2782

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Programmed cell death ligand 1 (PD-L1) expression is not a predominant feature in Ewing sarcomas.

Spurny C, Kailayangiri S, Jamitzky S, Altvater B, Wardelmann E, Dirksen U, Hardes J, Hartmann W, Rossig C
Pediatric blood & cancer 2018 Jan;65(1)