BS5915

RORC antibody from Bioworld Technology, Inc
NR1F3, RORG, RZRG, TOR

Antibody data

Product number
BS5915
Provider
Bioworld Technology, Inc
Product name
RORÎÛ polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS5915
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 114-159 of Human RORÎÛ.
Description
The nuclear orphan receptors RORÏ« and RORÎÛ are members of the nuclear hormone receptor superfamily. This family acts by directly associating with DNA sequences known as hormone response elements (HREs) and typically binds DNA as either homo- or heterodimers. RORÏ« and RORÎÛ are unique in that they bind DNA as monomers. RORÏ« has multiple isoforms that share common DNA- and putative ligand-binding domains, but differ in their aminoterminal domains, which are generated by alternative RNA processing. RORÎÛ comprises a 560 amino acid protein that shares 50% amino acid identity with RORÏ« and is most highly expressed in skeletal muscle. Although these proteins are considered ¡ùorphan receptors,¡ì due to a lack of defined ligands, experimental evidence has shown that melatonin may be the natural ligand for these nuclear receptors.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -