14-6988-80

RORC antibody from Invitrogen Antibodies
NR1F3, RORG, RZRG, TOR
Western blot
Supportive data in Antibodypedia
Immunoprecipitation
Recommended by provider

Antibody data

Product number
14-6988-80
Provider
Invitrogen Antibodies
Product name
Anti-ROR gamma (t) Monoclonal Antibody (AFKJS-9), eBioscience™
Provider product page
Invitrogen Antibodies - 14-6988-80
Antibody type
Monoclonal
Antigen
Other
Description
Description: The AFKJS-9 monoclonal antibody reacts with the mouse, human and rhesus monkey ROR gamma (t) protein. ROR gamma is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes ROR alpha and ROR beta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. ROR gamma is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, ROR gamma (t), which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ "double-positive" thymocytes, Th17 cells of the periphery and lymphoid tissue inducer (LTi) cells of lymphoid organs. The ROR gamma (t) isoform differs from ROR gamma by three unique amino acids at its amino terminus. Therefore, the AFKJS-9 antibody will react with both the ROR gamma and ROR gamma (t) isoforms. Applications Reported: This AFKJS-9 antibody has been reported for use in chromatin immunoprecipitation and western blotting. Applications Tested: This AFKJS-9 antibody has been tested by western blot analysis. This can be used at less than or equal to 5 µg per mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human, Mouse
Host
Rat
Isotype
IgG
Antibody clone number
AFKJS-9
Vial size
25 µg
Concentration
0.5 mg/mL
Storage
4° C
Provider Type Product Number
- No reagents -