Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01889G - Provider product page
- Provider
- Leading Biology
- Product name
- ZBTB7B / HcKrox Antibody (clone 7C12)
- Antibody type
- Monoclonal
- Description
- Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity).
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 7C12
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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