334601

antibody from BioLegend
Targeting: FCER1A FCE1A
Provider product page for 334601
Western blot
Immunocytochemistry
Flow cytometry

Antibody data

Product number
334601 - Provider product page
Provider
BioLegend
Product name
Purified anti-human FcŒRI‡
Antibody type
Monoclonal
Antigen
FceRIa
Description
High affinity IgE receptor (FcεRI) plays a key role in IgE-mediated allergic immune response. FcεRI is a tetrameric receptor complex, which is composed of one α-subunit (FcεRIα), one β-subunit, and two γ-subunits. FcεRIα directlybinds IgE with high affinity, while the β- and γ-chains are responsible for mediatingintracellular signals. FcεRIα is a 50 kD transmembrane protein with Ig superfamily structure. It is primarily found on mast cells and basophils. Further studies have indicated that FcεRIα is also expressed on many inflammatory cells including cutaneuos Langerhans cells, dendritic cells, monocytes of patients with allergic disorders, platelets, bronchial epithelial cells, eosinophils produced in hypereosinophilic syndrome, and neutrophils from allergy-induced asthma patients.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4° C.
FCER1A protein structure - 334601 shown in red.