Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN359442 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-serine/threonine Kinase 11 (STK11) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the N-terminal region of human STK11.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
- Concentration
- 0.25 mg/ml
- Storage
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.
Submitted references An efficient expression system for the production of functionally active human LKB1.
IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Martínez-Torrecuadrada JL, Romero S, Núñez A, Alfonso P, Sánchez-Céspedes M, Casal JI
Journal of biotechnology 2005 Jan 12;115(1):23-34
Journal of biotechnology 2005 Jan 12;115(1):23-34
IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.
Suzuki A, Kusakai G, Kishimoto A, Shimojo Y, Ogura T, Lavin MF, Esumi H
Biochemical and biophysical research communications 2004 Nov 19;324(3):986-92
Biochemical and biophysical research communications 2004 Nov 19;324(3):986-92
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of STK11 (arrow) using rabbit polyclonal STK11 Antibody (AP13926PU-N). 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected with the STK11 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue (breast carcinoma) reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
