PAB13231

antibody from Abnova Corporation

Targeting: NCSTN APH2, KIAA0253

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB13231

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB13231, RRID:AB_10553212

Product name

NCSTN polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of NCSTN.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Loss of nicastrin elicits an apoptotic phenotype in mouse embryos.

Nguyen V, Hawkins C, Bergeron C, Supala A, Huang J, Westaway D, St George-Hyslop P, Rozmahel R
Brain research 2006 May 1;1086(1):76-84

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Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.

Periz G, Fortini ME
Journal of neuroscience research 2004 Aug 1;77(3):309-22

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The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.

Selkoe DJ
Trends in cell biology 1998 Nov;8(11):447-53

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of NCSTN in mouse brain tissue lysate with NCSTN polyclonal antibody (Cat # PAB13231) at (A) 0.5, (B) 1, and (C) 2 ug/mL .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemistry of NCSTN in human brain tissue with NCSTN polyclonal antibody (Cat # PAB13231) at 5 ug/mL .

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)