BS8213

antibody from Bioworld Technology, Inc
Targeting: CD84 hCD84, mCD84, SLAMF5
Provider product page for BS8213
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8213 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD84 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CD84.
Description
The human CD84 gene maps to chromosome 1q24 and is composed of at least eight exons, with an exon coding for the 5' UTR and the leader peptide, two exons coding for each of the two extracellular Ig-like domains, an exon encoding the hydrophobic transmembrane region and four exons coding for the cytoplasmic domains. The extracellular Ig-like domains share structural and sequence homology with a group of members of the Ig superfamily that include CD2, CD48, CD58 and Ly9. Five CD84 isoforms have been characterized, including CD84a, CD84b, CD84c, CD84d and CD84e, which are preferentially expressed on B lymphocytes, monocytes and platelets, where they act as their own ligand and are therefore costimulatory molecules. The CD84 isoforms are generated by alternative exon enhancement, reading frame shift and use of cryptic splice sites. The differential expression of potential sites of phosphorylation on the different isoforms may be a way to regulate CD84 activity in signal transduction.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD84 protein structure - BS8213 shown in red.