AMM04185G

antibody from Leading Biology
Targeting: TEK CD202b, TIE-2, TIE2, VMCM, VMCM1
Provider product page for AMM04185G
Western blot

Antibody data

Product number
AMM04185G - Provider product page
Provider
Leading Biology
Product name
TEK Antibody (monoclonal) (M02)
Antibody type
Monoclonal
Description
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
3F8
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
TEK protein structure - AMM04185G shown in red.