AMM04186G

antibody from Leading Biology

Targeting: TEK CD202b, TIE-2, TIE2, VMCM, VMCM1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM04186G

Provider

Leading Biology

Product name

TEK Antibody (monoclonal) (M06)

Antibody type

Monoclonal

Description

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3C1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.