334202

antibody from BioLegend

Targeting: TEK CD202b, TIE-2, TIE2, VMCM, VMCM1

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: 334202 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#334202, RRID:AB_1134251
Product name: Purified anti-human CD202b (Tie2/Tek)
Antibody type: Monoclonal
Antigen: Recombinant extracellular domain of human Tie2
Description: CD202b is a 145 kD type I transmembrane protein, also known as Tie2 or TEK. It is a member of the receptor tyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator of CD202b to promote, maintain, and stabilize mature vessels and to maintain HSCs in quiescent state. Ang-2 is another ligand of CD202b, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie2 binds to Ang-4 as well.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

TEK protein structure - 334202 shown in red.