BS7418

antibody from Bioworld Technology, Inc

Targeting: ADAMTS4 ADAMTS-2, ADMP-1, KIAA0688

Immunohistochemistry

Antibody data

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Validation data

Product number: BS7418 - Provider product page
Provider: Bioworld Technology, Inc
Product name: ADAMTS4 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human ADAMTS4.
Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ADAMTS4 protein structure - BS7418 shown in red.