BS7381

antibody from Bioworld Technology, Inc

Targeting: FCGR3A CD16, CD16a, FCG3, FCGR3

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: BS7381 - Provider product page
Provider: Bioworld Technology, Inc
Product name: FCGR3A polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human FCGR3A.
Description: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Reactivity: Human
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

FCGR3A protein structure - BS7381 shown in red.