abx027925

antibody from Abbexa

Targeting: LMX1A LMX1, LMX1.1

No application information provided.

Antibody Data

Product number

abx027925

Provider

Abbexa

Product name

LIM Homeobox Transcription Factor 1-Alpha (Lmx1a) Antibody

Antibody type

Polyclonal

Description

Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.