abx015885

antibody from Abbexa

Targeting: HK1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx015885

Provider

Abbexa

Product name

Hexokinase 1 (HK1) Antibody

Antibody type

Monoclonal

Description

The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate.Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK).Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids.Glucokinase lacks the N-terminal hydrophobic cluster.The hydrophobic cluster is thought to be necessary for membrane binding.This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases.HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.