Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN394165 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-LIM Homeobox 4 (LHX4) (AA 208-307) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 208-307
- Isotype
- IgG
- Antibody clone number
- 2F3
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Mutation and gene copy number analyses of six pituitary transcription factor genes in 71 patients with combined pituitary hormone deficiency: identification of a single patient with LHX4 deletion.
Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies.
A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism.
The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4.
Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression.
Dateki S, Fukami M, Uematsu A, Kaji M, Iso M, Ono M, Mizota M, Yokoya S, Motomura K, Kinoshita E, Moriuchi H, Ogata T
The Journal of clinical endocrinology and metabolism 2010 Aug;95(8):4043-7
The Journal of clinical endocrinology and metabolism 2010 Aug;95(8):4043-7
Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies.
Pfaeffle RW, Hunter CS, Savage JJ, Duran-Prado M, Mullen RD, Neeb ZP, Eiholzer U, Hesse V, Haddad NG, Stobbe HM, Blum WF, Weigel JF, Rhodes SJ
The Journal of clinical endocrinology and metabolism 2008 Mar;93(3):1062-71
The Journal of clinical endocrinology and metabolism 2008 Mar;93(3):1062-71
A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism.
Castinetti F, Saveanu A, Reynaud R, Quentien MH, Buffin A, Brauner R, Kaffel N, Albarel F, Guedj AM, El Kholy M, Amin M, Enjalbert A, Barlier A, Brue T
The Journal of clinical endocrinology and metabolism 2008 Jul;93(7):2790-9
The Journal of clinical endocrinology and metabolism 2008 Jul;93(7):2790-9
The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4.
de Bruijn DR, van Dijk AH, Willemse MP, van Kessel AG
Oncogene 2008 Jan 24;27(5):653-62
Oncogene 2008 Jan 24;27(5):653-62
Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression.
Liu S, Luo H, Liu J, McNeilly AS, Cui S
Biochemical and biophysical research communications 2008 Feb 1;366(1):36-41
Biochemical and biophysical research communications 2008 Feb 1;366(1):36-41
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC