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- Antibody Data
- Antigen structure
- References [32]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 11187-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11187-1-AP, RRID:AB_2305523
- Product name
- ALPL antibody
- Antibody type
- Polyclonal
- Description
- ALPL antibody (Cat. #11187-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Cell dynamics in Hertwig's epithelial root sheath are regulated by β-catenin activity during tooth root development.
The effects of Omarigliptin on promoting osteoblastic differentiation.
Experimental study of expression profile and specific role of human microRNAs in regulating atrophic bone nonunion.
MicroRNA-21 promotes bone reconstruction in maxillary bone defects.
Neuropeptide Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3‑E1 cells via an autocrine mechanism.
Inhibition of vascular calcification by microRNA-155-5p is accompanied by the inactivation of TGF-β1/Smad2/3 signaling pathway.
VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
Metformin coordinates osteoblast/osteoclast differentiation associated with ischemic osteonecrosis.
Effect of MicroRNA-20a on Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells.
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.
Transcriptome analysis of gingival tissues of enamel-renal syndrome.
eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice.
Silver nanoparticles promote osteogenic differentiation of human periodontal ligament fibroblasts by regulating the RhoA-TAZ axis.
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Endothelial progenitor cells improve the therapeutic effect of mesenchymal stem cell sheets on irradiated bone defect repair in a rat model.
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Improvement of bone defect healing in rats via mesenchymal stem cell supernatant.
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Testicular acid phosphatase induces odontoblast differentiation and mineralization.
Osterix regulates tooth root formation in a site-specific manner.
Disruption of Tgfbr2 in odontoblasts leads to aberrant pulp calcification.
Magnesium ion implantation on a micro/nanostructured titanium surface promotes its bioactivity and osteogenic differentiation function.
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
β-catenin is required in odontoblasts for tooth root formation.
New population of odontoblasts responsible for tooth root formation.
BMP2/7 heterodimer is a stronger inducer of bone regeneration in peri-implant bone defects model than BMP2 or BMP7 homodimer.
Col1a1-cre mediated activation of β-catenin leads to aberrant dento-alveolar complex formation.
Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation.
Sun H, Dong J, Wang Y, Shen S, Shi Y, Zhang L, Zhao J, Sun X, Jiang Q
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Gu X, Li X, Jin Y, Zhang Z, Li M, Liu D, Wei F
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Cell dynamics in Hertwig's epithelial root sheath are regulated by β-catenin activity during tooth root development.
Yang S, Choi H, Kim TH, Jeong JK, Liu Y, Harada H, Cho ES
Journal of cellular physiology 2021 Jul;236(7):5387-5398
Journal of cellular physiology 2021 Jul;236(7):5387-5398
The effects of Omarigliptin on promoting osteoblastic differentiation.
Liao F, Hu X, Chen R
Bioengineered 2021 Dec;12(2):11837-11846
Bioengineered 2021 Dec;12(2):11837-11846
Experimental study of expression profile and specific role of human microRNAs in regulating atrophic bone nonunion.
Wei J, Chen H, Fu Y, Zhang B, Zhang L, Tao S, Lin F
Medicine 2020 Sep 4;99(36):e21653
Medicine 2020 Sep 4;99(36):e21653
MicroRNA-21 promotes bone reconstruction in maxillary bone defects.
Wang H, Wang H, Li X, Zhang Z, Zhao X, Wang C, Wei F
Journal of oral rehabilitation 2020 Nov;47 Suppl 1:4-11
Journal of oral rehabilitation 2020 Nov;47 Suppl 1:4-11
Neuropeptide Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3‑E1 cells via an autocrine mechanism.
Zhang B, Zhang X, Xiao J, Zhou X, Chen Y, Gao C
Molecular medicine reports 2020 Nov;22(5):4376-4382
Molecular medicine reports 2020 Nov;22(5):4376-4382
Inhibition of vascular calcification by microRNA-155-5p is accompanied by the inactivation of TGF-β1/Smad2/3 signaling pathway.
Zhao F, Wu Y, Yang W, Wu D, Wang C, Zhang F
Acta histochemica 2020 May;122(4):151551
Acta histochemica 2020 May;122(4):151551
VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.
Li Q, Lu F, Chen T, Zhang K, Lu Y, Li X, Wang Y, Liu L, Tian Q, Xiong F, Chen D
International journal of oral science 2020 Jul 31;12(1):22
International journal of oral science 2020 Jul 31;12(1):22
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
Cao X, Luo D, Li T, Huang Z, Zou W, Wang L, Lian K, Lin D
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37
Metformin coordinates osteoblast/osteoclast differentiation associated with ischemic osteonecrosis.
Park SH, Kang MA, Moon YJ, Jang KY, Kim JR
Aging 2020 Feb 11;12(6):4727-4741
Aging 2020 Feb 11;12(6):4727-4741
Effect of MicroRNA-20a on Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells.
Luo T, Yang X, Sun Y, Huang X, Zou L, Liu J
Cells, tissues, organs 2019;208(3-4):148-157
Cells, tissues, organs 2019;208(3-4):148-157
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.
Liu H, Dong Y, Feng X, Li L, Jiao Y, Bai S, Feng Z, Yu H, Li X, Zhao Y
Stem cell research & therapy 2019 Jun 18;10(1):180
Stem cell research & therapy 2019 Jun 18;10(1):180
Transcriptome analysis of gingival tissues of enamel-renal syndrome.
Wang YP, Lin HY, Zhong WL, Simmer JP, Wang SK
Journal of periodontal research 2019 Dec;54(6):653-661
Journal of periodontal research 2019 Dec;54(6):653-661
eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice.
Li J, Li X, Liu D, Hamamura K, Wan Q, Na S, Yokota H, Zhang P
Cell death & disease 2019 Dec 4;10(12):921
Cell death & disease 2019 Dec 4;10(12):921
Silver nanoparticles promote osteogenic differentiation of human periodontal ligament fibroblasts by regulating the RhoA-TAZ axis.
Xu Y, Zheng B, He J, Cui Z, Liu Y
Cell biology international 2019 Aug;43(8):910-920
Cell biology international 2019 Aug;43(8):910-920
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Yuan XJ, Wang YY, Shi BQ, Zhao YM
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;
Endothelial progenitor cells improve the therapeutic effect of mesenchymal stem cell sheets on irradiated bone defect repair in a rat model.
Liu H, Jiao Y, Zhou W, Bai S, Feng Z, Dong Y, Liu Q, Feng X, Zhao Y
Journal of translational medicine 2018 May 22;16(1):137
Journal of translational medicine 2018 May 22;16(1):137
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Liang D, Wang KJ, Tang ZQ, Liu RH, Zeng F, Cheng MY, Lian QS, Wu HK
Molecular medicine reports 2018 Jun;17(6):8269-8281
Molecular medicine reports 2018 Jun;17(6):8269-8281
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Xu C, Zhang H, Gu W, Wu H, Chen Y, Zhou W, Sun B, Shen X, Zhang Z, Wang Y, Liu Y, Yuan W
Scientific reports 2018 Jun 15;8(1):9225
Scientific reports 2018 Jun 15;8(1):9225
Improvement of bone defect healing in rats via mesenchymal stem cell supernatant.
Zhou W, Liu Q, Xu B
Experimental and therapeutic medicine 2018 Feb;15(2):1500-1504
Experimental and therapeutic medicine 2018 Feb;15(2):1500-1504
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Fan S, Gao X, Chen P, Li X
Life sciences 2018 Aug 15;207:205-211
Life sciences 2018 Aug 15;207:205-211
Testicular acid phosphatase induces odontoblast differentiation and mineralization.
Choi H, Kim TH, Yun CY, Kim JW, Cho ES
Cell and tissue research 2016 Apr;364(1):95-103
Cell and tissue research 2016 Apr;364(1):95-103
Osterix regulates tooth root formation in a site-specific manner.
Kim TH, Bae CH, Lee JC, Kim JE, Yang X, de Crombrugghe B, Cho ES
Journal of dental research 2015 Mar;94(3):430-8
Journal of dental research 2015 Mar;94(3):430-8
Disruption of Tgfbr2 in odontoblasts leads to aberrant pulp calcification.
Ahn YH, Kim TH, Choi H, Bae CH, Yang YM, Baek JA, Lee JC, Cho ES
Journal of dental research 2015 Jun;94(6):828-35
Journal of dental research 2015 Jun;94(6):828-35
Magnesium ion implantation on a micro/nanostructured titanium surface promotes its bioactivity and osteogenic differentiation function.
Wang G, Li J, Zhang W, Xu L, Pan H, Wen J, Wu Q, She W, Jiao T, Liu X, Jiang X
International journal of nanomedicine 2014;9:2387-98
International journal of nanomedicine 2014;9:2387-98
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Gu GJ, Chen T, Zhou HM, Sun KX, Li J
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
β-catenin is required in odontoblasts for tooth root formation.
Kim TH, Bae CH, Lee JC, Ko SO, Yang X, Jiang R, Cho ES
Journal of dental research 2013 Mar;92(3):215-21
Journal of dental research 2013 Mar;92(3):215-21
New population of odontoblasts responsible for tooth root formation.
Bae CH, Kim TH, Chu JY, Cho ES
Gene expression patterns : GEP 2013 Jun-Jul;13(5-6):197-202
Gene expression patterns : GEP 2013 Jun-Jul;13(5-6):197-202
BMP2/7 heterodimer is a stronger inducer of bone regeneration in peri-implant bone defects model than BMP2 or BMP7 homodimer.
Sun P, Wang J, Zheng Y, Fan Y, Gu Z
Dental materials journal 2012;31(2):239-48
Dental materials journal 2012;31(2):239-48
Col1a1-cre mediated activation of β-catenin leads to aberrant dento-alveolar complex formation.
Kim TH, Bae CH, Jang EH, Yoon CY, Bae Y, Ko SO, Taketo MM, Cho ES
Anatomy & cell biology 2012 Sep;45(3):193-202
Anatomy & cell biology 2012 Sep;45(3):193-202
Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation.
Kim TH, Lee JY, Baek JA, Lee JC, Yang X, Taketo MM, Jiang R, Cho ES
Biochemical and biophysical research communications 2011 Sep 9;412(4):549-55
Biochemical and biophysical research communications 2011 Sep 9;412(4):549-55
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 11187-1-AP(ALPL antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11187-1-AP(ALPL antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11187-1-AP(ALPL antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ALPL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ALPL. This antibody recognizes human,mouse,rat antigen. The ALPL antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
