BS6134

antibody from Bioworld Technology, Inc
Targeting: ALPL HOPS, TNALP, TNAP, TNSALP
Provider product page for BS6134
Western blot
Immunohistochemistry

Antibody data

Product number
BS6134 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TNAP / ALPL polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TNAP / ALPL.
Description
Alkaline phosphatases (AP) are glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallated glycoproteins that catalyze the hydrolysis of phospho-monoesters into an inorganic phosphate and an alcohol. There are at least four distinct but related alkaline phosphatases: intestinal (IAP), placental (PLAP), placental-like (ALP-1 or GCAP) and tissue non-specific (TNAP). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. TNAP is widely expressed in liver, kidney, bone, stomach and colon, and is therefore referred to as the tissue non-specific form of AP. TNAP, in conjuntion with plasma cell membrane glycoprotein-1, function in bone mineralization; however, mice that lack a functional form of TNAP show normal skeletal development.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ALPL protein structure - BS6134 shown in red.