60067

antibody from STEMCELL Technologies Inc

Targeting: ALPL HOPS, TNALP, TNAP, TNSALP

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

60067

Provider

STEMCELL Technologies Inc

Product name

Anti-Human TRA-2-54 Antibody, Clone TRA-2-54/2J

Antibody type

Monoclonal

Description

The TRA-2-54/2J antibody reacts with the tissue non-specific isoform of alkaline phosphatase (AP), which is expressed at high levels in undifferentiated pluripotent stem cells such as human and mouse embryonic stem (ES) cells, as well as induced pluripotent stem (iPS) and embryonal carcinoma (EC) cells. This isozyme of AP is the same as that expressed by liver, bone and kidney cells. Levels of AP decrease upon differentiation and, thus, the TRA-2-54/2J antibody can be used to monitor the differentiation status of pluripotent stem cells. The TRA-2-54/2J antibody does not cross-react with other isozymes of AP, which differ through post-translational modification, and reportedly does not recognize AP from cow, dog, goat, Guinea pig, hamster, mouse, rat or sheep, or Old World Monkeys such as the rhesus monkey, baboon and African green monkey.

Reactivity

Human, Porcine, Rabbit

Isotype

IgG

Vial size

100 µg

Storage

2 - 8°C