abx010331

antibody from Abbexa

Targeting: MAP4K4 FLH21957, HGK, NIK

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx010331

Provider

Abbexa

Product name

MEK Kinase Kinase 4 (MAP4K4) Antibody

Antibody type

Monoclonal

Description

A Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.