Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP1-88881 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-88881, RRID:AB_11031499
- Product name
- Rabbit Polyclonal ULK2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human ULK2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Methylation silencing of ULK2, an autophagy gene, is essential for astrocyte transformation and tumor growth.
Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, Settleman J, Stephanopoulos G, Dyson NJ, Zoncu R, Ramaswamy S, Haas W, Bardeesy N
Nature 2015 Aug 20;524(7565):361-5
Nature 2015 Aug 20;524(7565):361-5
Methylation silencing of ULK2, an autophagy gene, is essential for astrocyte transformation and tumor growth.
Shukla S, Patric IR, Patil V, Shwetha SD, Hegde AS, Chandramouli BA, Arivazhagan A, Santosh V, Somasundaram K
The Journal of biological chemistry 2014 Aug 8;289(32):22306-18
The Journal of biological chemistry 2014 Aug 8;289(32):22306-18
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ULK2 Antibody [NBP1-88881] - Analysis in human cell line SH-SY5Y.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ULK2 Antibody [NBP1-88881] - Analysis in control (vector only transfected HEK293T lysate) and ULK2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ULK2 Antibody [NBP1-88881] - Staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ULK2 Antibody [NBP1-88881] - Staining of human urinary bladder shows cytoplasmic and membranous positivity in urothelial cells.