CABT-B11811

antibody from Creative Diagnostics

Targeting: MAP3K20 MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B11811

Provider

Creative Diagnostics

Product name

Mouse anti-Human ZAK monoclonal antibody, clone 4H6

Antibody type

Monoclonal

Description

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4H6

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.