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- Product number
- ABIN395143 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-320) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 231-320
- Isotype
- IgG
- Antibody clone number
- 1G10
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references PLU-1/JARID1B overexpression predicts proliferation properties in head and neck squamous cell carcinoma.
JARID1B protein expression and prognostic implications in uveal melanoma.
The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity.
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Defining the human deubiquitinating enzyme interaction landscape.
Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Cui Z, Song L, Hou Z, Han Y, Hu Y, Wu Y, Chen W, Mao L
Oncology reports 2015 May;33(5):2454-60
Oncology reports 2015 May;33(5):2454-60
JARID1B protein expression and prognostic implications in uveal melanoma.
Radberger P, Radberger A, Bykov VJ, Seregard S, Economou MA
Investigative ophthalmology & visual science 2012 Jul 3;53(8):4442-9
Investigative ophthalmology & visual science 2012 Jul 3;53(8):4442-9
The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity.
Yao W, Peng Y, Lin D
Biochemical and biophysical research communications 2010 May 28;396(2):323-8
Biochemical and biophysical research communications 2010 May 28;396(2):323-8
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
Roesch A, Fukunaga-Kalabis M, Schmidt EC, Zabierowski SE, Brafford PA, Vultur A, Basu D, Gimotty P, Vogt T, Herlyn M
Cell 2010 May 14;141(4):583-94
Cell 2010 May 14;141(4):583-94
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, Field HI, Kelly JD, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R
Molecular cancer 2010 Mar 13;9:59
Molecular cancer 2010 Mar 13;9:59
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell 2009 Jul 23;138(2):389-403
Cell 2009 Jul 23;138(2):389-403
Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A
European journal of human genetics : EJHG 2009 Dec;17(12):1650-7
European journal of human genetics : EJHG 2009 Dec;17(12):1650-7
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Supportive validation
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- ELISA
Supportive validation
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- IHC
