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- Antibody Data
- Antigen structure
- References [3]
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- Western blot [2]
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- Product number
- PAB9975 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB9975, RRID:AB_1706704
- Product name
- TP53BP2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of TP53BP2.
- Isotype
- IgG
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references ASPP [corrected] and cancer.
Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53.
The ASPP family: deciding between life and death after DNA damage.
Trigiante G, Lu X
Nature reviews. Cancer 2006 Mar;6(3):217-26
Nature reviews. Cancer 2006 Mar;6(3):217-26
Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53.
Liu ZJ, Lu X, Zhang Y, Zhong S, Gu SZ, Zhang XB, Yang X, Xin HM
FEBS letters 2005 Mar 14;579(7):1587-90
FEBS letters 2005 Mar 14;579(7):1587-90
The ASPP family: deciding between life and death after DNA damage.
Slee EA, Lu X
Toxicology letters 2003 Apr 4;139(2-3):81-7
Toxicology letters 2003 Apr 4;139(2-3):81-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot using TP53BP2 polyclonal antibody (Cat # PAB9975) to detect over-expressed TP53BP2 in MCF-7 cells (Lane 2, arrowhead).Lane 1 is a non-transfected control.Lane 3 is MCF-7 cells over-expressing PPP1R13B.Cell extracts were electrophoresed and transferred to nitrocellulose.The membrane was probed with the primary antibody at a 1 : 1,000 dilution.The identity of the lower MW band at approximately 40 KDa is unknown.Personal Communication, H. Yang, Univ. Oklahoma, Oklahoma City, OK.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot using TP53BP2 polyclonal antibody (Cat # PAB9975) to detect over-expressed TP53BP2 in MCF-7 cells (Lane 2, arrowhead).Lane 1 is a non-transfected control.Lane 3 is MCF-7 cells over-expressing PPP1R13B.Cell extracts were electrophoresed and transferred to nitrocellulose.The membrane was probed with the primary antibody at a 1 : 1,000 dilution.The identity of the lower MW band at approximately 40 KDa is unknown.Personal Communication, H. Yang, Univ. Oklahoma, Oklahoma City, OK.
