Ab086727

antibody from Aladdin Scientific Corporation

Targeting: TP53BP2 53BP2, ASPP2, PPP1R13A

Western blot (Data presented on provider website)

Antibody Data

Product number

Ab086727

Provider

Aladdin Scientific Corporation

Product name

Recombinant 53BP2/ASPP2 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human 53BP2/ASPP2 Antibody, Recombinant (R09-1B5), could be used for WB and so on.ApplicationWB: 1/500-1/1000Protein Function Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 20-84


Antibody clone number

R09-1B5

Vial size

100μl,10μl,1ml,50μl

Concentration

0,33 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.