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- References [21]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12330-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12330-2-AP, RRID:AB_2140101
- Product name
- TAK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TAK1 antibody (Cat. #12330-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, hamster, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Hamster
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Hepatic P38 Activation Modulates Systemic Metabolism Through Fgf21-Mediated Interorgan Communication.
CARS senses cysteine deprivation to activate AMPK for cell survival.
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Mycobacterium tuberculosis protein kinase G acts as an unusual ubiquitinating enzyme to impair host immunity.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Recombinant Dual-target MDM2/MDMX Inhibitor Reverses Doxorubicin Resistance through Activation of the TAB1/TAK1/p38 MAPK Pathway in Wild-type p53 Multidrug-resistant Breast Cancer Cells.
Inducible MicroRNA-217 Inhibits NF-κB- and IRF3-Driven Immune Responses in Lower Vertebrates through Targeting TAK1.
Protein phosphatase 6 is a key factor regulating spermatogenesis.
TRIM14 promotes endothelial activation via activating NF-κB signaling pathway.
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
JAZF1 Suppresses Papillary Thyroid Carcinoma Cell Proliferation and Facilitates Apoptosis via Regulating TAK1/NF-κB Pathways.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure.
Quantitative proteomic dissection of a native 14-3-3ε interacting protein complex associated with hepatocellular carcinoma.
Zhang X, Kong Z, Xu X, Yun X, Chao J, Ding D, Li T, Gao Y, Guan N, Zhu C, Qin X
Journal of Cancer 2021;12(7):1926-1935
Journal of Cancer 2021;12(7):1926-1935
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Hepatic P38 Activation Modulates Systemic Metabolism Through Fgf21-Mediated Interorgan Communication.
Liu W, Sun C, Yan Y, Cao H, Niu Z, Shen S, Liu S, Wu Y, Li Y, Hui L, Li Y, Zhao L, Hu C, Ding Q, Jiang J, Ying H
Diabetes 2021 Oct 21;
Diabetes 2021 Oct 21;
CARS senses cysteine deprivation to activate AMPK for cell survival.
Yuan M, Yan R, Zhang Y, Qiu Y, Jiang Z, Liu H, Wang Y, Sun L, Zhang H, Gao P
The EMBO journal 2021 Nov 2;40(21):e108028
The EMBO journal 2021 Nov 2;40(21):e108028
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Ma X, Li X, Di Q, Zhao X, Zhang R, Xiao Y, Sun P, Tang H, Quan J, Xiao W, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543
Mycobacterium tuberculosis protein kinase G acts as an unusual ubiquitinating enzyme to impair host immunity.
Wang J, Ge P, Lei Z, Lu Z, Qiang L, Chai Q, Zhang Y, Zhao D, Li B, Su J, Peng R, Pang Y, Shi Y, Zhang Y, Gao GF, Qiu XB, Liu CH
EMBO reports 2021 Jun 4;22(6):e52175
EMBO reports 2021 Jun 4;22(6):e52175
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Li Q, Li S, Xu C, Zhao J, Hou L, Jiang F, Zhu Z, Wang Y, Tian L
Cell biology and toxicology 2021 Jul 31;
Cell biology and toxicology 2021 Jul 31;
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Zhang X, Nie Q, Zhang Z, Zhao J, Zhang F, Wang C, Wang X, Song G
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Recombinant Dual-target MDM2/MDMX Inhibitor Reverses Doxorubicin Resistance through Activation of the TAB1/TAK1/p38 MAPK Pathway in Wild-type p53 Multidrug-resistant Breast Cancer Cells.
Fan Y, Ma K, Jing J, Wang C, Hu Y, Shi Y, Li E, Geng Q
Journal of Cancer 2020;11(1):25-40
Journal of Cancer 2020;11(1):25-40
Inducible MicroRNA-217 Inhibits NF-κB- and IRF3-Driven Immune Responses in Lower Vertebrates through Targeting TAK1.
Zhang L, Chu Q, Chang R, Xu T
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 15;205(6):1620-1632
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 15;205(6):1620-1632
Protein phosphatase 6 is a key factor regulating spermatogenesis.
Lei WL, Han F, Hu MW, Liang QX, Meng TG, Zhou Q, Ouyang YC, Hou Y, Schatten H, Wang ZB, Sun QY
Cell death and differentiation 2020 Jun;27(6):1952-1964
Cell death and differentiation 2020 Jun;27(6):1952-1964
TRIM14 promotes endothelial activation via activating NF-κB signaling pathway.
Huang X, Li Y, Li X, Fan D, Xin HB, Fu M
Journal of molecular cell biology 2020 Apr 24;12(3):176-189
Journal of molecular cell biology 2020 Apr 24;12(3):176-189
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Fan Y, Li M, Ma K, Hu Y, Jing J, Shi Y, Li E, Dong D
Cancer biology & therapy 2019;20(5):617-632
Cancer biology & therapy 2019;20(5):617-632
JAZF1 Suppresses Papillary Thyroid Carcinoma Cell Proliferation and Facilitates Apoptosis via Regulating TAK1/NF-κB Pathways.
Huang L, Cai Y, Luo Y, Xiong D, Hou Z, Lv J, Zeng F, Yang Y, Cheng X
OncoTargets and therapy 2019;12:10501-10514
OncoTargets and therapy 2019;12:10501-10514
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, Zuo Q, Zhou Y, Cao Z, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, Hao H, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2017 May 1;198(9):3690-3704
Journal of immunology (Baltimore, Md. : 1950) 2017 May 1;198(9):3690-3704
Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure.
Zhou H, Gao S, Duan X, Liang S, Scott DA, Lamont RJ, Wang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Sep;29(9):3737-49
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Sep;29(9):3737-49
Quantitative proteomic dissection of a native 14-3-3ε interacting protein complex associated with hepatocellular carcinoma.
Bai C, Tang S, Bai C, Chen X
Amino acids 2014 Apr;46(4):841-52
Amino acids 2014 Apr;46(4):841-52
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 12330-2-AP(MAP3K7 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TAK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TAK1. This antibody recognizes human, hamster, mouse antigen. The TAK1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
